currently available urine-based tumour markers in the detection of new and recurrent urothelial bladder cancer
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چکیده
منابع مشابه
Urine markers for detection and surveillance of bladder cancer.
OBJECTIVES Bladder cancer detection and surveillance includes cystoscopy and cytology. Urinary cytology is limited by its low sensitivity for low-grade tumors. Urine markers have been extensively studied to help improve the diagnosis of bladder cancer with the goal of complementing or even replacing cystoscopy. However, to date, no marker has reached widespread use owing to insufficient evidenc...
متن کاملDetection of recurrent bladder cancer: NMP22 test or urine cytology?
PURPOSE To assess the accuracy of voided urine cytology versus urinary nuclear matrix protein 22 (NMP22) qualitative assay in the diagnosis of various grades and stages of recurrent bladder transitional cell carcinoma (TCC). MATERIALS AND METHODS From July 2007 to February 2009, all patients with history of superficial bladder TCC were included in this multi-center study. Each patient provide...
متن کاملIdentification of microRNAs in blood and urine as tumour markers for the detection of urinary bladder cancer.
Since differential expression of microRNAs (miRNAs) has been found to be highly associated with several types of cancer, the goal of the present study was to identify an miRNA fingerprint as a non‑invasive diagnostic tool to detect urinary bladder cancer using the easily accessible samples of whole blood and urine. Blood and urine samples from 4 controls and from patients suffering from superfi...
متن کاملEpigenetic Markers for Bladder Cancer in Urine
Many tumor markers for bladder cancer have been evaluated for use in detecting and monitoring bladder cancers tissue specimens, bladder washes, and urine specimens. However, none of the biomarkers reported to date has shown sufficient sensitivity and specificity to detect the entire spectrum of bladder cancers in routine clinical practice. The limited value of the established prognostic markers...
متن کاملUrine and bladder washing cytology for detection of urothelial carcinoma: standard test with new possibilities
BACKGROUND Light microscopic evaluation of cell morphology in preparations from urine or bladder washing containing exfoliated cells is a standard and primary method for the detection of bladder cancer and also malignancy from other parts of the urinary tract. The cytopathologic examination is a valuable method to detect an early recurrence of malignancy or new primary carcinoma during the foll...
متن کاملMethylation Markers for Urine-Based Detection of Bladder Cancer: The Next Generation of Urinary Markers for Diagnosis and Surveillance of Bladder Cancer
Cancer of the urinary bladder is the fifth most common neoplasm in the industrialized countries. Diagnosis and surveillance are dependent on invasive evaluation with cystoscopy and to some degree cytology as an adjunct analysis. Nomuscle invasive bladder cancer is characterized by frequent recurrences after resection, and up to 30% will develop an aggressive phenotype. The journey towards a non...
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عنوان ژورنال:
nephro-urology monthlyجلد ۴، شماره ۱، صفحات ۳۴۵-۳۴۹
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